Right-click the x360ce.exe file and select "Run as administrator." This is often the simplest fix for permission-related failures.
Here’s what specifically means in this context and how to fix it.
Some third-party antivirus (Avast, McAfee, Bitdefender) actively blocks x360ce's "self-protection" feature because it looks like ransomware behavior (a program trying to modify its own executables). self protection failed error code 4 x360ce 2021
Windows Defender or third-party AVs mistake the x360ce DLL hooks for malware.
Finally, the "DLL shuffling" technique was a common workaround. x360ce comes with various DLL filenames (e.g., xinput1_3.dll , xinput1_4.dll , xinput9_1_0.dll ). Games are programmed to look for specific filenames. By renaming the DLL, users could sometimes bypass the protection check, as different DLL versions interacted with the Windows DirectX architecture in slightly different ways. Right-click the x360ce
Under Virus & threat protection settings , click .
If running as admin didn't work, the virtual driver itself is likely the culprit. Here’s how to give it a fresh start. Windows Defender or third-party AVs mistake the x360ce
Disclaimer: Some of these solutions involve modifying system security settings. Please proceed with caution. If you are still having issues, please let me know: What are you trying to play?